Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20181931 | 0.83 | SLC6A2 (0.43) | SLC6A2PARP1MTNR1AL3MBTL1CYP2C19 | |
| SCHEMBL20181945 | 0.80 | PARP1 (0.41) | SLC6A2PARP1MTNR1AL3MBTL1CYP2C19 | |
| SCHEMBL4235557 | 0.75 | ADA (0.39) | SLC6A2PARP1MTNR1AL3MBTL1CYP2C19 | |
| SCHEMBL598048 | 0.75 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL8135638 | 0.72 | PARP1 (0.47) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL8134942 | 0.72 | PARP1 (0.44) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL30991276 | 0.72 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL23938013 | 0.72 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL26634121 | 0.71 | PARP1 (0.38) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL26634094 | 0.71 | PARP1 (0.38) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | TYK2, JAK3, JAK1 | SLC6A2 3405/4885PARP1 2064/4885MTNR1A 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.