Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP8 | P22894 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168498 | 0.90 | SPR (0.51) | TRPV1SPRHDAC3HDAC1HDAC2 | |
| SCHEMBL20168496 | 0.90 | SPR (0.51) | TRPV1SPRHDAC3HDAC1HDAC2 | |
| SCHEMBL1131628 | 0.86 | TRPV1 (0.72) | TRPV1SPRFAAHPTGS2 | |
| SCHEMBL28314856 | 0.86 | TRPV1 (0.58) | TRPV1SPRFAAHPTGS2 | |
| SCHEMBL28314855 | 0.86 | TRPV1 (0.58) | TRPV1SPRFAAHPTGS2 | |
| SCHEMBL21470293 | 0.84 | TRPV1 (0.70) | TRPV1SPRFAAHPTGS2 | |
| SCHEMBL20182419 | 0.84 | TRPV1 (0.70) | TRPV1SPRFAAHPTGS2 | |
| SCHEMBL3813867 | 0.83 | TRPV1 (0.57) | TRPV1SPR | |
| SCHEMBL3816115 | 0.83 | TRPV1 (0.57) | TRPV1SPR | |
| SCHEMBL23552961 | 0.82 | SPR (0.70) | TRPV1SPRFAAHPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |