Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165518 | 0.76 | MEN1 (0.49) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL3341020 | 0.76 | TDP1 (0.67) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL17545679 | 0.75 | TDP1 (0.53) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL14006538 | 0.74 | TDP1 (0.51) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL4394882 | 0.74 | MEN1 (0.53) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL9573730 | 0.73 | TDP1 (0.55) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL14365835 | 0.73 | EPHX1 (0.57) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL16800926 | 0.73 | TDP1 (0.55) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL1760969 | 0.73 | MEN1 (0.59) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL46654 | 0.73 | TDP1 (0.58) | MEN1GAAKMT2ATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091467-A2 | A SIMULTANEOUSLY ANTIMICROBIAL AND PROTEIN-REPELLENT POLYZWITTERION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2018-05-24 | — | — | WO | disclosed |