SCHEMBL4394882

SCHEMBL4394882

CC(C)(C)OC(=O)NCCNC(=O)CCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.51
EPHX1 P07099 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
CYP3A4 P08684 1/20 0.41
MALT1 Q9UDY8 1/20 0.40
IDO1 P14902 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
KDM4E B2RXH2 1/20 0.39
KDM5C P41229 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4388456 0.92 MEN1 (0.46) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL16061043 0.91 MEN1 (0.53) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL5041833 0.91 MEN1 (0.51) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL1509861 0.91 MEN1 (0.45) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL23034976 0.91 MEN1 (0.45) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL28348827 0.90 TDP1 (0.54) MEN1GAAKMT2ATDP1EPHX1
Succinic Acid SCHEMBL29429364 0.89 GAA (0.56) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL1509845 0.88 MEN1 (0.50) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL1509910 0.88 MEN1 (0.50) MEN1GAAKMT2ATDP1EPHX1
SCHEMBL156911 0.86 GAA (0.58) MEN1GAAKMT2ATDP1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-07-03 US disclosed
CN-114901315-B Fibroblast Activation Protein (FAP) -targeted imaging and treatment of cancer and other fibrotic and inflammatory diseases 普渡研究基金会 2025-04-29 CN disclosed
US-20220409747-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES PURDUE RESEARCH FOUNDATION 2022-12-29 US disclosed
US-20220409747-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES PURDUE RESEARCH FOUNDATION 2022-12-29 US disclosed
CN-114901315-A Fibroblast Activation Protein (FAP) -targeted imaging and treatment of cancer and other fibrotic and inflammatory diseases 普渡研究基金会 2022-08-12 CN disclosed
EP-4031184-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES Purdue Research Foundation (US) 2022-07-27 EP disclosed
US-20210096081-A1 POLYMER DYE FOR DETECTING HYDROGEN PEROXIDE AND STRUCTURE FOR DETECTING HYDROGEN PEROXIDE CANON KABUSHIKI KAISHA (JP) 2021-04-01 US disclosed
WO-2021055641-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES PURDUE RESEARCH FOUNDATION (US) 2021-03-25 WO disclosed
US-20120308646-A1 TETRACYCLIC ANTHRAQUINONES POSSESSING ANTI-CANCER PROPERTIES ZHANG HESHENG (CN) 2012-12-06 US disclosed
US-20090325894-A1 TETRACYCLIC ANTHRAQUINONES POSSESSING ANTI-CANCER PROPERTIES ZHANG HESHENG 2009-12-31 US disclosed
EP-2123283-A1 THE TETRACYCLIC ANTHRAQUINONES POSSESSING ANTI-CANCER EFFECT Tianjin Hemey Bio-Tech Co., Ltd. (CN) 2009-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R MEN1 601/4885GAA 3092/4885KMT2A 3160/4885
US-20090325894-A1 TETRACYCLIC ANTHRAQUINONES POSSESSING ANTI-CANCER PROPERTIES GLS2, GLS, VIP MEN1 838/4885GAA 1032/4885KMT2A 3262/4885
US-20120308646-A1 TETRACYCLIC ANTHRAQUINONES POSSESSING ANTI-CANCER PROPERTIES ALAD, SLC27A2, ANTXR2 MEN1 2676/4885GAA 703/4885KMT2A 3885/4885
US-20220409747-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES FAP, FIBP, FGFR1 MEN1 1279/4885GAA 282/4885KMT2A 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.