Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26777524 | 0.77 | HSP90AA1 (0.32) | CYP2D6CYP1A2CYP3A4TSHRHSD17B10 | |
| SCHEMBL20182449 | 0.72 | ADORA3 (0.36) | MKNK2CYP3A4TSHRHSD17B10ALDH1A1 | |
| SCHEMBL28570261 | 0.71 | CYP2D6 (0.38) | MKNK2CYP2D6CYP1A2CYP3A4TSHR | |
| SCHEMBL30656419 | 0.71 | CYP2D6 (0.38) | MKNK2CYP2D6CYP1A2CYP3A4TSHR | |
| SCHEMBL20182463 | 0.69 | TNKS2 (0.32) | TNKS2 | |
| SCHEMBL20182601 | 0.69 | ADORA3 (0.38) | CYP3A4TSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL18545322 | 0.68 | GDA (0.43) | MEN1KMT2A | |
| SCHEMBL19035767 | 0.68 | GDA (0.30) | — | |
| SCHEMBL26644771 | 0.65 | MKNK2 (0.36) | MKNK2TNKS2CDC25B | |
| SCHEMBL26644767 | 0.65 | CYP1A2 (0.33) | MKNK2CYP2D6CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-05-07 | — | — | US | disclosed |
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | PNP, PDE7A, PDE2A | MKNK2 3178/4885CYP2D6 508/4885CYP1A2 98/4885 |
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | PNP, PDE7A, PDE2A | MKNK2 3178/4885CYP2D6 508/4885CYP1A2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.