Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378778 | 0.94 | APLNR (0.87) | APLNR | |
| SCHEMBL20183091 | 0.94 | APLNR (0.87) | APLNR | |
| SCHEMBL20168699 | 0.88 | APLNR (1.00) | APLNR | |
| SCHEMBL20172531 | 0.88 | APLNR (1.00) | APLNR | |
| SCHEMBL20168634 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL20168635 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL21378674 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL20183048 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL20166483 | 0.84 | APLNR (1.00) | APLNR | |
| SCHEMBL20166485 | 0.84 | APLNR (1.00) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093576-A1 | ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-24 | — | — | WO | disclosed |