Dimethylformamide

Dimethylformamide

SCHEMBL20183466

CCC(=O)CC.CN(C)C=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.59
TSHR P16473 2/20 0.53
ALDH1A1 P00352 3/20 0.35
FFAR3 O14843 1/20 0.35
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL28083529 0.95 TDP1 (0.53) TDP1TSHRALDH1A1FFAR3USP2
Propionic Acid SCHEMBL27702359 0.82 FFAR3 (0.59) TDP1TSHRALDH1A1FFAR3USP2
Butanone SCHEMBL959887 0.82 ALDH1A1 (0.59) TDP1TSHRALDH1A1FFAR3USP2
Butanone SCHEMBL8041248 0.82 ALDH1A1 (0.59) TDP1TSHRALDH1A1FFAR3USP2
Butanone SCHEMBL1627455 0.82 ALDH1A1 (0.59) TDP1TSHRALDH1A1FFAR3USP2
Propionamide SCHEMBL25390733 0.80 TSHR (0.50) TDP1TSHRALDH1A1FFAR3USP2
Dimethylformamide SCHEMBL849515 0.78
Formic Acid SCHEMBL9576744 0.78
Dimethylformamide SCHEMBL28338245 0.77
SCHEMBL42679 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947336-B2 Moisture curable hot melt urethane composition, method for producing cured foam of same, synthetic leather and method for producing synthetic leather DIC CORPORATION (JP) 2021-03-16 US disclosed
EP-3327054-B1 MOISTURE CURABLE HOT MELT URETHANE COMPOSITION, METHOD FOR PRODUCING CURED FOAM OF SAME, SYNTHETIC LEATHER AND METHOD FOR PRODUCING SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2020-11-11 EP disclosed
US-20190055339-A1 MOISTURE CURABLE HOT MELT URETHANE COMPOSITION, METHOD FOR PRODUCING CURED FOAM OF SAME, SYNTHETIC LEATHER AND METHOD FOR PRODUCING SYNTHETIC LEATHER DIC CORPORATION (JP) 2019-02-21 US disclosed
EP-3327054-A1 MOISTURE CURABLE HOT MELT URETHANE COMPOSITION, METHOD FOR PRODUCING CURED FOAM OF SAME, SYNTHETIC LEATHER AND METHOD FOR PRODUCING SYNTHETIC LEATHER DIC Corporation (JP) 2018-05-30 EP disclosed