SCHEMBL20183976

SCHEMBL20183976

C=C(C)C(=O)OCC(C)(COC(=O)C(=C)C)N=C=S

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
THRB P10828 1/20 0.37
ALDH1A1 P00352 3/20 0.35
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL152350 0.84 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL19468924 0.77 TSHR (0.37) TSHRTHRBALDH1A1
SCHEMBL28177724 0.74 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1851512 0.74 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL51592 0.73 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL396824 0.73 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL15337 0.73 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL20183943 0.73 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL17933327 0.71 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL5712202 0.71 TSHR (0.41) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed