Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569230 | 0.82 | SMN1; SMN2 (0.48) | KDM4EALDH1A1MAPTSMN1; SMN2HCAR2 | |
| SCHEMBL30042917 | 0.82 | SMN1; SMN2 (0.48) | KDM4EALDH1A1MAPTSMN1; SMN2HCAR2 | |
| Hydrochloric Acid SCHEMBL1452738 | 0.80 | LMNA (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2HCAR2 | |
| SCHEMBL20184144 | 0.75 | PDE3B (0.39) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL287450 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1MAPTHCAR2PKM | |
| SCHEMBL29526925 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1MAPTHCAR2PKM | |
| Hydrochloric Acid SCHEMBL5755935 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1MAPTHCAR2PKM | |
| SCHEMBL3701660 | 0.68 | PDE3B (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29434463 | 0.68 | PDE3B (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5684624 | 0.67 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325446-A1 | SUBSTITUTED ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |