Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 9/20 | 1.00 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235621 | 0.94 | PRMT1 (0.88) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8235643 | 0.94 | PRMT1 (0.88) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL20184765 | 0.93 | PRMT1 (0.86) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL12711215 | 0.88 | PRMT1 (0.79) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8238368 | 0.87 | PRMT1 (0.77) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8235330 | 0.83 | PRMT1 (1.00) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8235629 | 0.82 | PRMT1 (0.86) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL12736178 | 0.82 | PRMT1 (0.69) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8300739 | 0.80 | PRMT1 (0.66) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL9575289 | 0.79 | PRMT1 (0.64) | PRMT1NISCHTOP2ATOP2BBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |