SCHEMBL9575289

SCHEMBL9575289

C(=Cc1ccc(C2=NCCN2)cc1)c1ccc(C2=NCCN2)cc1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.64
NISCH Q9Y2I1 10/20 0.63
BLM P54132 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
LMNA P02545 1/20 0.61
RECQL P46063 1/20 0.61
TOP2A P11388 2/20 0.59
TOP2B Q02880 2/20 0.59
HTR1D P28221 1/20 0.58
ADRA1A P35348 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23902117 0.90 PRMT1 (0.59) PRMT1NISCHBLMTDP1LMNA
SCHEMBL5476725 0.87 NISCH (0.79) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL27619343 0.85 NISCH (0.59) NISCHBLMTDP1LMNARECQL
SCHEMBL3532726 0.85 NISCH (0.65) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL23902308 0.84 NISCH (0.55) PRMT1NISCHBLMTDP1TOP2A
SCHEMBL8194859 0.84 NISCH (0.58) PRMT1NISCHBLMTDP1LMNA
SCHEMBL8194858 0.84 NISCH (0.58) PRMT1NISCHBLMTDP1LMNA
SCHEMBL3532943 0.82 NISCH (0.65) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL27850837 0.81 BLM (0.53) PRMT1NISCHBLMTDP1LMNA
SCHEMBL23901781 0.80 NISCH (0.58) PRMT1NISCHBLMTDP1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331507-B1 POLYVINYL CHLORIDE PLASTISOL COMPOSITION ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
US-4977201-A Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings ASAHI DENKA KOGYO K.K. (JP) 1990-12-11 US disclosed
EP-0331507-A1 Polyvinyl chloride plastisol composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1989-09-06 EP disclosed