Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 11/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979972 | 0.92 | PRMT1 (0.88) | PRMT1APPF2F10PLG | |
| SCHEMBL8815310 | 0.92 | PRMT1 (0.88) | PRMT1APPF2F10PLG | |
| SCHEMBL17084488 | 0.92 | PRMT1 (0.88) | PRMT1APPF2F10PLG | |
| SCHEMBL20184763 | 0.92 | PRMT1 (1.00) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL12412056 | 0.87 | PRMT1 (1.00) | PRMT1F2F10 | |
| SCHEMBL8229718 | 0.86 | PRMT1 (0.89) | PRMT1F2F10PLGPLAU | |
| SCHEMBL8229699 | 0.85 | PRMT1 (0.86) | PRMT1F2F10PLGPLAU | |
| SCHEMBL20184756 | 0.80 | PRMT1 (1.00) | PRMT1F2F10PLGPLAU | |
| SCHEMBL5516771 | 0.79 | PRMT1 (0.78) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL8229704 | 0.79 | PRMT1 (1.00) | PRMT1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |