Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ASIC1 | P78348 | 3/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.53 |
| ▸ | FURIN | P09958 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238115 | 0.77 | ESR1 (0.42) | — | |
| SCHEMBL13940984 | 0.73 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL5703072 | 0.67 | ASIC1 (0.81) | KCNH2ASIC1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16993671 | 0.65 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29438748 | 0.64 | NPFFR2 (1.00) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL5703122 | 0.64 | GRIN2D (0.68) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16993712 | 0.64 | NPFFR2 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16993741 | 0.64 | NPFFR2 (1.00) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL914608 | 0.64 | GRIN2D (1.00) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5523773 | 0.64 | ESR1 (0.53) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |