Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20982698 | 0.97 | PRMT1 (0.56) | PRMT1MEN1KMT2ARECQLKDM4E | |
| SCHEMBL14669392 | 0.94 | PRMT1 (0.53) | PRMT1MEN1KMT2ARECQLKDM4E | |
| SCHEMBL13204584 | 0.89 | NISCH (0.54) | PRMT1RECQLNISCHLMNA | |
| SCHEMBL20982791 | 0.87 | PKN1 (0.64) | PRMT1MEN1KMT2ARECQLKDM4E | |
| SCHEMBL24312987 | 0.85 | GAA (0.56) | MEN1KMT2ARECQLKDM4EALDH1A1 | |
| SCHEMBL8842675 | 0.85 | TOP2A (0.56) | PRMT1ALDH1A1HPGDHSD17B10NISCH | |
| SCHEMBL13167162 | 0.84 | TOP2A (0.63) | PRMT1ALDH1A1HPGDHSD17B10NISCH | |
| SCHEMBL21900562 | 0.82 | MEN1 (0.59) | PRMT1MEN1KMT2ARECQLKDM4E | |
| SCHEMBL14599548 | 0.81 | PRMT1 (0.49) | PRMT1NISCH | |
| SCHEMBL21856214 | 0.81 | MEN1 (0.48) | PRMT1MEN1KMT2ARECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |