Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6978627 | 0.71 | OPRL1 (0.47) | OPRL1NR3C1 | |
| SCHEMBL2504705 | 0.69 | SYK (0.41) | OPRL1NR3C1 | |
| SCHEMBL1356638 | 0.68 | OPRL1 (0.53) | OPRL1 | |
| SCHEMBL14860791 | 0.68 | OPRL1 (0.35) | OPRL1 | |
| Alcohol SCHEMBL6978770 | 0.67 | OPRL1 (0.46) | OPRL1NR3C1 | |
| SCHEMBL29946411 | 0.67 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL14862888 | 0.67 | MEN1 (0.35) | OPRL1 | |
| SCHEMBL9049933 | 0.65 | BACE1 (0.37) | OPRL1 | |
| SCHEMBL31206791 | 0.65 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL899396 | 0.64 | UGT2B7 (0.37) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075517-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |