Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549303 | 0.98 | HTT (0.70) | HTTKMT2AMEN1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL244803 | 0.92 | HTT (0.79) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL28418371 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL22654486 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL26665328 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL23293675 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL22654483 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| Miripirium SCHEMBL22654466 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| SCHEMBL28630114 | 0.90 | HTT (0.85) | HTTKMT2AMEN1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL26106948 | 0.90 | HTT (0.76) | HTTKMT2AMEN1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745604-B2 | Compositions comprising phase change materials and methods of making the same | PHASE CHANGE ENERGY SOLUTIONS, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20180148621-A1 | Compositions Comprising Phase Change Materials and Methods of Making the Same | PHASE CHANGE ENERGY SOLUTIONS, INC. | 2018-05-31 | — | — | US | disclosed |