SCHEMBL20185675

SCHEMBL20185675

CC(C)N=C(NCCCCCCNCCCCCCNC(=NC(C)C)NC(C)C)NC(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.41
KDM1A O60341 3/20 0.40
PAOX Q6QHF9 1/20 0.32
MAOB P27338 2/20 0.31
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
EPHX2 P34913 1/20 0.30
HRH2 P25021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19971131 0.94 KDM1A (0.46) EPHX1KDM1AALDH1A1
SCHEMBL13380623 0.94 KDM1A (0.46) EPHX1KDM1AALDH1A1
SCHEMBL20473417 0.94 EPHX1 (0.44) EPHX1KDM1AALDH1A1KDM4EMAPK1
SCHEMBL22068820 0.94 EPHX1 (0.44) EPHX1KDM1AALDH1A1KDM4EMAPK1
SCHEMBL22068793 0.94 EPHX1 (0.44) EPHX1KDM1AALDH1A1KDM4EMAPK1
SCHEMBL20473413 0.94 EPHX1 (0.44) EPHX1KDM1AALDH1A1KDM4EMAPK1
SCHEMBL22068794 0.93 KDM1A (0.44) EPHX1KDM1AALDH1A1
SCHEMBL22068787 0.92 EPHX1 (0.41) EPHX1KDM1AALDH1A1KDM4EMAPK1
SCHEMBL20185667 0.91 KDM1A (0.43) EPHX1KDM1AALDH1A1
SCHEMBL22068805 0.88 EPHX1 (0.37) EPHX1KDM1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3795649-A2 CATALYST WITH POLYSILOXANE STRUCTURE UNIT FOR CURABLE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2021-03-24 EP disclosed
EP-3294803-B1 GUANIDINE GROUP CONTAINING CATALYST SIKA TECH AG (CH) 2020-12-09 EP disclosed
US-10836868-B2 Catalyst having a polysiloxane structural unit for hardenable compositions SIKA TECHNOLOGY AG (CH) 2020-11-17 US disclosed
EP-3131992-B1 FAST CURING MIGRATION-FREE COMPOSITION BASED ON POLYMERS CONTAINING SILANE GROUPS SIKA TECH AG (CH) 2020-06-17 EP disclosed
US-10414875-B2 Catalyst containing guanidine groups SIKA TECHNOLOGY AG (CH) 2019-09-17 US disclosed
US-20180327549-A1 CATALYST HAVING A POLYSILOXANE STRUCTURAL UNIT FOR HARDENABLE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2018-11-15 US disclosed
US-20180148545-A1 CATALYST CONTAINING GUANIDINE GROUPS SIKA TECHNOLOGY AG (CH) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10414875-B2 Catalyst containing guanidine groups GMPS, GMNN, RNMT EPHX1 2367/4885KDM1A 200/4885PAOX 3607/4885
US-20180148545-A1 CATALYST CONTAINING GUANIDINE GROUPS GMPS, RNMT, GMNN EPHX1 2252/4885KDM1A 229/4885PAOX 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.