Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.58 |
| ▸ | DGKA | P23743 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12232837 | 0.98 | EPHX2 (0.60) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL18209370 | 0.98 | EPHX2 (0.60) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20185950 | 0.97 | EPHX2 (0.58) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL12179613 | 0.97 | EPHX2 (0.61) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL14760438 | 0.97 | EPHX2 (0.61) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20185982 | 0.94 | MGLL (0.61) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL17586415 | 0.94 | EPHX2 (0.57) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL12179602 | 0.93 | MGLL (0.68) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL14759657 | 0.93 | MGLL (0.68) | EPHX2DGKAMGLLMAPTALDH1A1 | |
| SCHEMBL6072564 | 0.92 | CNR2 (0.64) | EPHX2DGKAMGLLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107801395-B | Process for preparing amphiphilic imidazolinium compounds | 拜耳动物保健有限责任公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-3292106-B1 | PROCESS FOR THE PREPARATION OF AMPHIPHILIC IMIDAZOLINIUM COMPOUNDS | BAYER ANIMAL HEALTH GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-10479768-B2 | Process for the preparation of amphiphilic imidazolinium compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2019-11-19 | — | — | US | disclosed |
| US-20180148415-A1 | IMPROVED PROCESS FOR THE PREPARATION OF AMPHIPHILIC IMIDAZOLINIUM COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479768-B2 | Process for the preparation of amphiphilic imidazolinium compounds | IPO8, IPO9, IPO7 | EPHX2 1872/4885DGKA 99/4885MGLL 198/4885 |
| US-20180148415-A1 | IMPROVED PROCESS FOR THE PREPARATION OF AMPHIPHILIC IMIDAZOLINIUM COMPOUNDS | IPO8, IPO9, IPO7 | EPHX2 2297/4885DGKA 62/4885MGLL 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.