Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263628 | 0.88 | ESR1 (0.53) | TSHRMAPK1TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL2020911 | 0.86 | SIGMAR1 (0.43) | TSHRPOLBMAPK1TAAR1SIGMAR1 | |
| SCHEMBL1868728 | 0.85 | TSHR (0.64) | TSHRPOLBMAPK1TAAR1SIGMAR1 | |
| SCHEMBL28115795 | 0.82 | TAAR1 (0.52) | TSHRPOLBMAPK1TAAR1SIGMAR1 | |
| SCHEMBL3047457 | 0.80 | TSHR (0.67) | TSHRPOLBMAPK1TAAR1SIGMAR1 | |
| SCHEMBL1842356 | 0.79 | TSHR (0.47) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1838330 | 0.79 | TSHR (0.43) | TSHRPOLBMAPK1TAAR1GABRA1 | |
| SCHEMBL1347498 | 0.79 | TSHR (0.60) | TSHRPOLBMAPK1TAAR1SIGMAR1 | |
| Benzene SCHEMBL1835281 | 0.77 | TSHR (0.68) | TSHRPOLBSLC6A2GABRA1GABRB2 | |
| SCHEMBL1840949 | 0.76 | TSHR (0.45) | TSHRPOLBMAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110521291-A | Carrier film and method for manufacturing electronic component | MURATA MANUFACTURING CO | 2019-11-29 | — | — | CN | disclosed |
| CN-110461909-A | HIGH HEAT POLYCARBONATE AND POLYETHERIMIDE-SILOXANE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF | SABIC GLOBAL TECHNOLOGIES BV | 2019-11-15 | — | — | CN | disclosed |
| CN-110088198-A | High flow, ductile poly (aliphatic ester-carbonate) compositions | 沙特基础工业全球技术有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106604967-B | Flame-retarded heat-conducting polymer composition with good flowability characteristics and application thereof | 沙特基础工业全球技术公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109715691-A | Anisotropic composite material based on polyisocyanates | 科思创德国股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108752593-B | A kind of preparation method and applications of polysiloxane-polycarbonate | 广东伟的新材料股份有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109240060-A | Image forming apparatus and image forming method | 柯尼卡美能达株式会社 | 2019-01-18 | — | — | CN | disclosed |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| EP-0364792-B1 | CARRIER FOR DYEING POLYESTER MATERIALS | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |
| US-4994089-A | Synergistic | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0364792-A2 | Carrier for dyeing polyester materials | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | TSHR 2998/4885POLB 4314/4885MAPK1 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.