Styrene

Styrene

SCHEMBL20186899

C=CC(=O)OC(C)N.C=Cc1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
PTGS2 P35354 1/20 0.38
THRB P10828 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
CYP2C19 P33261 1/20 0.36
AKT1 P31749 1/20 0.35
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34
LMNA P02545 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28494530 0.87 TSHR (0.48) ALDH1A1TSHRPTGS2THRBHCAR2
Styrene SCHEMBL27904886 0.83 HCAR2 (0.58) ALDH1A1TSHRPTGS2THRBHCAR2
SCHEMBL117941 0.80
Styrene SCHEMBL10663818 0.80 ALDH1A1 (0.41) ALDH1A1TSHRPTGS2THRBHCAR2
Styrene SCHEMBL8982592 0.80 TSHR (0.41) ALDH1A1TSHRPTGS2THRBHCAR2
(Chloromethyl)Benzene SCHEMBL27131605 0.80 TSHR (0.41) ALDH1A1TSHRTHRBHCAR2CYP2C19
Styrene SCHEMBL8518132 0.80 ALDH1A1 (0.48) ALDH1A1TSHRPTGS2THRBHCAR2
Styrene SCHEMBL27455883 0.80 ALDH1A1 (0.48) ALDH1A1TSHRPTGS2THRBHCAR2
Styrene SCHEMBL28767758 0.79 ALDH1A1 (0.56) ALDH1A1TSHRPTGS2CYP2C19ADRA2A
Styrene SCHEMBL7882644 0.79 ALDH1A1 (0.56) ALDH1A1TSHRPTGS2CYP2C19ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10394147-B2 Electrostatic latent image developing toner KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-27 US disclosed
US-10241431-B2 Toner KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-03-26 US disclosed
US-20180348655-A1 ELECTROSTATIC LATENT IMAGE DEVELOPING TONER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-12-06 US disclosed
US-20180149991-A1 TONER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-05-31 US disclosed