Styrene

Styrene

SCHEMBL20186900

C=CC(=O)OCCN.C=Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.55
TSHR P16473 6/20 0.45
ALDH1A1 P00352 5/20 0.45
TP53 P04637 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AKR1B10 O60218 3/20 0.42
AKR1B1 P15121 3/20 0.42
IDO1 P14902 1/20 0.42
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
APP P05067 1/20 0.36
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3043271 0.90 THRB (0.67) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL6236168 0.85 TSHR (0.63) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL28274716 0.85 THRB (0.57) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL379434 0.84 THRB (0.55) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL18818305 0.84 TSHR (0.61) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL10809429 0.83 TSHR (0.56) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL27516788 0.83 THRB (0.54) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL10970647 0.83 TSHR (0.59) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL27678634 0.81 THRB (0.51) THRBTSHRALDH1A1TP53HIF1A
Styrene SCHEMBL10663822 0.81 THRB (0.85) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10394147-B2 Electrostatic latent image developing toner KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-27 US disclosed
US-10241431-B2 Toner KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-03-26 US disclosed
US-20180348655-A1 ELECTROSTATIC LATENT IMAGE DEVELOPING TONER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-12-06 US disclosed
US-20180149991-A1 TONER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-05-31 US disclosed