Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | CCNC | P24863 | 4/20 | 0.50 |
| ▸ | CDK8 | P49336 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048540 | 0.81 | PDK2 (0.55) | CCNCCDK8BRD4CHEK1PDK2 | |
| SCHEMBL30527143 | 0.78 | SLC22A12 (0.54) | SLC22A12CCNCCDK8AURKAAURKB | |
| SCHEMBL23753783 | 0.77 | PDK2 (0.48) | BRD4IKBKETBK1PDK2GRM2 | |
| SCHEMBL28978238 | 0.74 | AURKB (0.50) | SLC22A12CCNCCDK8BRD4AURKA | |
| SCHEMBL30288907 | 0.74 | AURKB (0.50) | SLC22A12CCNCCDK8BRD4AURKA | |
| SCHEMBL14840407 | 0.74 | CCNC (0.57) | SLC22A12CCNCCDK8BRD4AURKA | |
| SCHEMBL18491331 | 0.73 | CCNC (0.73) | SLC22A12CCNCCDK8CDK19 | |
| SCHEMBL18491330 | 0.73 | CCNC (0.73) | SLC22A12CCNCCDK8CDK19 | |
| SCHEMBL27982333 | 0.73 | ALDH1A1 (0.49) | SLC22A12IKBKEMAPTMKNK1MKNK2 | |
| SCHEMBL18491821 | 0.72 | CCNC (0.68) | SLC22A12CCNCCDK8MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-05-31 | — | — | US | disclosed |
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-05-31 | — | — | US | disclosed |
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | BRCA1, NQO2, NQO1 | SLC22A12 3369/4885CCNC 130/4885CDK8 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.