SCHEMBL20186961

SCHEMBL20186961

Cc1ccc(CS(=O)(=O)Nc2ccc(N)c(C(F)(F)F)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.67
FFAR1 O14842 3/20 0.51
AR P10275 1/20 0.43
KMT2A Q03164 1/20 0.40
RORC P51449 2/20 0.39
KIF11 P52732 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20186980 0.81 SLC22A12 (0.54) FFAR4ARRORC
SCHEMBL20186985 0.81 AR (0.48) FFAR4ARRORC
SCHEMBL28543669 0.80 FFAR4 (1.00) FFAR4FFAR1KMT2A
SCHEMBL20186977 0.80 NPC1 (0.49) FFAR4ARKMT2A
SCHEMBL20186974 0.80 KMT2A (0.43) FFAR4ARKMT2ARORC
SCHEMBL20186983 0.75 FFAR4 (0.39) FFAR4KMT2ARORC
SCHEMBL28537715 0.74 FFAR4 (1.00) FFAR4FFAR1KMT2A
SCHEMBL20186995 0.74 SLC22A12 (0.54) FFAR4ARRORC
SCHEMBL20186962 0.74 AR (0.42) FFAR4ARRORCKIF11
SCHEMBL28534522 0.70 FFAR4 (0.67) FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10905120-B2 ABA receptor agonists that modulate transpiration THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-02 US disclosed
US-20180146666-A1 ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10905120-B2 ABA receptor agonists that modulate transpiration ADORA2A, ADORA1, AAK1 FFAR4 47/4885FFAR1 13/4885AR 1334/4885
US-20180146666-A1 ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION ADORA2A, ADORA1, AAK1 FFAR4 47/4885FFAR1 13/4885AR 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.