Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229403 | 0.77 | AKR1B1 (0.37) | AKR1B1KMT2AMEN1SMN1; SMN2PYCR1 | |
| SCHEMBL20186999 | 0.73 | POLB (0.45) | ALDH1A1POLBRORC | |
| SCHEMBL20186966 | 0.72 | POLB (0.41) | ALDH1A1POLBRORC | |
| SCHEMBL20186984 | 0.71 | ALDH1A1 (0.50) | KMT2AGAAMEN1MAPTALDH1A1 | |
| SCHEMBL18571257 | 0.70 | AKR1B1 (0.45) | AKR1B1MAPTPYCR1P2RX7NMT1 | |
| SCHEMBL20186960 | 0.68 | POLB (0.41) | GAAALDH1A1POLBRORC | |
| SCHEMBL12982381 | 0.68 | AKR1B1 (0.51) | AKR1B1KMT2APYCR1P2RX7CHRM5 | |
| SCHEMBL30797087 | 0.68 | AKR1B1 (0.51) | AKR1B1KMT2APYCR1P2RX7CHRM5 | |
| SCHEMBL20187000 | 0.68 | ALDH1A1 (0.40) | KMT2AGAAMEN1MAPTSMN1; SMN2 | |
| SCHEMBL20186981 | 0.66 | POLB (0.39) | BCAT2ALDH1A1POLBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-02 | — | — | US | disclosed |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | ADORA2A, ADORA1, AAK1 | AKR1B1 819/4885PGR 2797/4885AR 1334/4885 |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | ADORA2A, ADORA1, AAK1 | AKR1B1 819/4885PGR 2797/4885AR 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.