Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925165 | 0.91 | PARP1 (0.37) | DDR1NPC1RAB9APARP1FFAR1 | |
| SCHEMBL19341929 | 0.88 | DDR1 (0.37) | DDR1NPC1RAB9AKDM4EFFAR1 | |
| SCHEMBL20209681 | 0.86 | FFAR1 (0.39) | DDR1NPC1RAB9APARP1KDM4E | |
| SCHEMBL20209536 | 0.85 | SCD (0.43) | DDR1NPC1RAB9APARP1KDM4E | |
| SCHEMBL20209492 | 0.84 | DDR1 (0.35) | DDR1NPC1RAB9APARP1FFAR1 | |
| SCHEMBL20829884 | 0.84 | PARP1 (0.35) | DDR1NPC1RAB9APARP1FFAR1 | |
| SCHEMBL20209530 | 0.84 | TRPA1 (0.37) | DDR1NPC1RAB9APARP1FFAR1 | |
| SCHEMBL20209680 | 0.84 | DDR1 (0.37) | DDR1NPC1RAB9APARP1FFAR1 | |
| SCHEMBL20209282 | 0.83 | TRPA1 (0.39) | DDR1NPC1RAB9APARP1KDM4E | |
| SCHEMBL17732142 | 0.82 | DDR1 (0.33) | DDR1NPC1RAB9AKDM4EPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018095795-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-31 | — | — | WO | disclosed |