Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187536 | 0.70 | TRPA1 (0.53) | TRPA1 | |
| SCHEMBL23718289 | 0.69 | TRPA1 (0.48) | TRPA1 | |
| SCHEMBL20187454 | 0.66 | POLB (0.47) | TRPA1 | |
| SCHEMBL23718222 | 0.66 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL22194603 | 0.63 | TRPA1 (0.73) | TRPA1 | |
| SCHEMBL22194600 | 0.63 | TRPA1 (0.73) | TRPA1 | |
| SCHEMBL22194604 | 0.63 | TRPA1 (0.73) | TRPA1 | |
| SCHEMBL22194729 | 0.63 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL22195018 | 0.62 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL22195020 | 0.62 | TRPA1 (1.00) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544979-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018096159-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-31 | — | — | WO | disclosed |