SCHEMBL20187699

SCHEMBL20187699

NCCCCS(=O)(=O)NCCc1ccc(F)c(OCC2CC2)c1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 19/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20189248 0.99 DUT (0.52) DUT
SCHEMBL20188135 0.97 DUT (0.54) DUT
SCHEMBL20187693 0.89 DUT (0.45) DUT
SCHEMBL20196472 0.88 DUT (0.41) DUT
SCHEMBL20188821 0.87 DUT (0.42) DUT
SCHEMBL20196513 0.84 DUT (0.48) DUT
SCHEMBL20190360 0.82 DUT (0.49) DUT
SCHEMBL20191185 0.82 DUT (0.66) DUT
SCHEMBL20188374 0.82 DUT (0.49) DUT
SCHEMBL20193325 0.82 DUT (0.49) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098206-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
WO-2018098208-A1 NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
WO-2018098204-A1 6-MEMBERED URACIL ISOSTERES CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed