Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL14157405 | 1.00 | GSR (0.48) | GSRGABRR1RNPEPSLC7A5LTA4H | |
| Alanine SCHEMBL12520564 | 0.90 | GSR (0.58) | GSRGABRR1RNPEPSLC7A5LTA4H | |
| Alanine SCHEMBL15655229 | 0.87 | GSR (0.56) | GSRGABRR1RNPEPSLC7A5CPB2 | |
| Alanine SCHEMBL28071526 | 0.87 | GABRR1 (0.52) | GSRGABRR1SLC7A5LTA4HGABRP | |
| Alanine SCHEMBL28071528 | 0.87 | GABRR1 (0.52) | GSRGABRR1SLC7A5LTA4HGABRP | |
| 1,6-Hexanediol SCHEMBL15656018 | 0.84 | GPR84 (0.48) | GABRR1SLC7A5LTA4HLMNAKMT2A | |
| 1,6-Hexanediol SCHEMBL15656017 | 0.84 | GPR84 (0.48) | GABRR1SLC7A5LTA4HLMNAKMT2A | |
| Alanine SCHEMBL20740651 | 0.84 | GABRR1 (0.55) | GSRGABRR1SLC7A5LTA4HGABRP | |
| Alanine SCHEMBL15655432 | 0.83 | GAA (0.41) | GSRGABRR1RNPEPSLC7A5LTA4H | |
| Alanine SCHEMBL27624409 | 0.83 | GSR (0.46) | GSRGABRR1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544635-A2 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| CN-110234357-A | Contain peptide linker for antibody-drug conjugates | 梅尔莎纳医疗公司 | 2019-09-13 | — | — | CN | disclosed |
| WO-2018098269-A2 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2018-05-31 | — | — | WO | disclosed |