Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 6/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190349 | 0.88 | DUT (0.49) | DUTMTNR1ANPC1RAB9AKDM5A | |
| SCHEMBL22723246 | 0.81 | DUT (0.57) | DUTACACBACACA | |
| SCHEMBL22723247 | 0.81 | DUT (0.57) | DUTACACBACACA | |
| SCHEMBL20188108 | 0.76 | DUT (0.45) | DUTMTNR1ACYP2D6KCNH2 | |
| SCHEMBL20188045 | 0.76 | DUT (0.51) | DUTMTNR1ANPC1RAB9AAKR1C3 | |
| SCHEMBL20191169 | 0.73 | DUT (0.59) | DUT | |
| SCHEMBL20187896 | 0.72 | DUT (0.50) | DUTMTNR1AACACBACACAKDM5A | |
| SCHEMBL1409587 | 0.71 | CHRM2 (0.60) | ACACBACACAKDM5AKDM4C | |
| SCHEMBL1408705 | 0.71 | DUT (0.65) | DUT | |
| SCHEMBL13606412 | 0.71 | DUT (0.62) | DUTKDM5AKDM4CNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |