⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125812 | 0.84 | — | — | |
| SCHEMBL14146669 | 0.77 | — | — | |
| SCHEMBL14146676 | 0.77 | — | — | |
| SCHEMBL838455 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL15214380 | 0.76 | ALDH1A1 (0.33) | — | |
| Tert-Pentylsilanetriol SCHEMBL838171 | 0.76 | — | — | |
| SCHEMBL839385 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL686782 | 0.75 | — | — | |
| SCHEMBL18866726 | 0.73 | — | — | |
| SCHEMBL14557372 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148587-B1 | CARBONITRILE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10328082-B2 | Methods of use and combinations | PFIZER INC. (US) | 2019-06-25 | — | — | US | disclosed |
| WO-2017183043-A1 | NOVEL PROCESS FOR THE PREPARATION OF TAVABOROLE, ITS NOVEL POLYMORPHIC FORMS AND THE POLYMORPHS THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2017-10-26 | — | — | WO | disclosed |
| US-9777287-B2 | Nucleotide sequences and corresponding polypeptides conferring modified phenotype characteristics in plants | CERES, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| EP-2576492-B1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORP (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20170252352-A1 | METHODS OF USE AND COMBINATIONS | PFIZER INC. (US) | 2017-09-07 | — | — | US | disclosed |
| US-9755204-B2 | Separator, electrode element, electric energy storage device and method for producing separator | NEC CORPORATION (JP) | 2017-09-05 | — | — | US | disclosed |
| WO-2017143041-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2017-08-24 | — | — | WO | disclosed |
| EP-2925725-B1 | NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER (US) | 2016-11-09 | — | — | EP | disclosed |
| US-9433621-B2 | Substituted pyridine and pyrimidine derivatives and their use in treating viral infections | MERCK SHARP & DOHME CORP. (US) | 2016-09-06 | — | — | US | disclosed |
| US-8762067-B2 | Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data | THE INVENTION SCIENCE FUND I, LLC (US) | 2014-06-24 | — | — | US | disclosed |
| US-20140155390-A1 | NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-8728436-B2 | Synthesis strategy toward microspheric carbon coated off-stoichiometric lithium—iron—phosphorus compound materials | HEFEI GUOXUAN HIGH-TECH POWER ENERGY CO., LTD. (CN) | 2014-05-20 | — | — | US | disclosed |
| EP-2249829-B1 | Tetrahydropyridoethers for treatment of age-related macular degeneration (AMD) | KATAIRO GMBH (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-8545806-B2 | Compositions and methods for biological remodeling with frozen particle compositions | THE INVENTION SCIENCE FUND I, LLC (US) | 2013-10-01 | — | — | US | disclosed |
| US-8541631-B2 | Surface treatment method for solid material | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20130171095-A1 | Method for Purifying Antibodies | XENCOR, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130144919-A1 | TEMPLATE DEVELOPMENT BASED ON REPORTED ASPECTS OF A PLURALITY OF SOURCE USERS | SEARETE LLC (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2341108-A1 | Surface treatment method for solid material | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-07-06 | — | — | EP | disclosed |
| US-20110160464-A1 | SURFACE TREATMENT METHOD FOR SOLID MATERIAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-06-30 | — | — | US | disclosed |