Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 18/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188101 | 1.00 | APLNR (0.42) | APLNR | |
| SCHEMBL23549420 | 1.00 | APLNR (0.42) | APLNR | |
| SCHEMBL22466686 | 0.86 | APLNR (0.41) | APLNR | |
| SCHEMBL20188389 | 0.86 | APLNR (0.41) | APLNR | |
| SCHEMBL20189068 | 0.85 | APLNR (0.42) | APLNR | |
| SCHEMBL22319051 | 0.85 | APLNR (0.33) | APLNR | |
| SCHEMBL20187872 | 0.85 | APLNR (0.42) | APLNR | |
| SCHEMBL20189087 | 0.85 | APLNR (0.45) | APLNR | |
| SCHEMBL20190001 | 0.85 | APLNR (0.45) | APLNR | |
| SCHEMBL20188558 | 0.85 | APLNR (0.45) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541792-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | Amgen Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |