Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326057 | 1.00 | KDM4E (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL2024691 | 0.99 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL1768511 | 0.99 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2023336 | 0.99 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL12638001 | 0.95 | KDM4E (0.62) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL2019858 | 0.91 | KDM4E (0.61) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10669670 | 0.91 | KDM4E (0.57) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL2024689 | 0.89 | KDM4E (0.56) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL12638276 | 0.89 | KDM4E (0.56) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9773701 | 0.89 | KDM4E (0.58) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753925-A | Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | claimed |
| EP-0155587-B1 | 1,7-DIAMINO-1,4-DIHYDRO-4-OXO-3(AZA)QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING BACTERIAL DISEASES | BAYER AG (DE) | 1988-06-08 | — | — | EP | claimed |
| EP-0155587-A1 | 1,7-Diamino-1,4-dihydro-4-oxo-3(aza)quinoline-carboxylic acids, process for their preparation and their use in treating bacterial diseases | BAYER AG (DE) | 1985-09-25 | — | — | EP | claimed |
| EP-2501680-B1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2016-02-10 | — | — | EP | disclosed |
| EP-2501680-B1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2016-02-10 | — | — | EP | disclosed |
| EP-2332916-A2 | A process for a preparation of marbofloxacin and intermediate thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-06-15 | — | — | EP | disclosed |
| EP-2332916-A2 | A process for a preparation of marbofloxacin and intermediate thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-06-15 | — | — | EP | disclosed |
| WO-2011061292-A1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2011-05-26 | — | — | WO | disclosed |
| EP-0155587-B1 | 1,7-DIAMINO-1,4-DIHYDRO-4-OXO-3(AZA)QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING BACTERIAL DISEASES | BAYER AG (DE) | 1988-06-08 | — | — | EP | disclosed |
| EP-0155587-A1 | 1,7-Diamino-1,4-dihydro-4-oxo-3(aza)quinoline-carboxylic acids, process for their preparation and their use in treating bacterial diseases | BAYER AG (DE) | 1985-09-25 | — | — | EP | disclosed |