Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649231 | 0.96 | KDM4E (0.54) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL2018897 | 0.91 | KDM4E (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL31326057 | 0.91 | KDM4E (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL13694455 | 0.91 | KDM4E (0.50) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL2024691 | 0.90 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL1768511 | 0.90 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2023336 | 0.90 | KDM4E (0.69) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL12638282 | 0.89 | KDM4E (0.51) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9773701 | 0.87 | KDM4E (0.58) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9535838 | 0.87 | KDM4E (0.48) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522718-B | A kind of synthetic method of Marbofloxacin | 浙江国邦药业有限公司 | 2019-11-08 | — | — | CN | claimed |
| EP-2501680-B1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2016-02-10 | — | — | EP | disclosed |
| EP-2501680-B1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2016-02-10 | — | — | EP | disclosed |
| EP-2340809-A2 | A medicament containing fluoroquinolones | Bayer Animal Health GmbH (DE) | 2011-07-06 | — | — | EP | disclosed |
| EP-2332916-A2 | A process for a preparation of marbofloxacin and intermediate thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-06-15 | — | — | EP | disclosed |
| EP-2332916-A2 | A process for a preparation of marbofloxacin and intermediate thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-06-15 | — | — | EP | disclosed |
| WO-2011061292-A1 | A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2011-05-26 | — | — | WO | disclosed |
| US-5892040-A | Process for the manufacture of a tricyclic compound | PFIZER. INC (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0680482-B1 | PROCESS FOR THE MANUFACTURE OF A TRICYCLIC COMPOUND | PFIZER (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0680482-A1 | PROCESS FOR THE MANUFACTURE OF A TRICYCLIC COMPOUND. | PFIZER (US) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017074-A1 | PROCESS FOR THE MANUFACTURE OF A TRICYCLIC COMPOUND | PFIZER INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| EP-0259804-B1 | Pyrido[3,2,1-ij]-1,3,4-benzoxadiazine derivatives, process for their preparation, resulting pharmaceutical preparations and intermediates for use in the process | HOFFMANN LA ROCHE (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4864023-A | MICROBIOCIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4801584-A | ANTIMICROBIAL | HOFFMANN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0259804-A2 | Pyrido[3,2,1-ij]-1,3,4-benzoxadiazine derivatives, process for their preparation, resulting pharmaceutical preparations and intermediates for use in the process | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-16 | — | — | EP | disclosed |