SCHEMBL20189374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20189379	1.00	CXCR4 (0.39)	CXCR4FABP1FABP6KDM4ECYP1A2
	SCHEMBL18296935	0.83	GRIN2B (0.40)	KDM4EGRIN2BSSTR4ALDH1A1HRH4
	SCHEMBL20189218	0.83	GRIN2B (0.40)	KDM4EGRIN2BSSTR4ALDH1A1HRH4
	SCHEMBL20189215	0.83	GRIN2B (0.40)	KDM4EGRIN2BSSTR4ALDH1A1HRH4
	SCHEMBL20189772	0.83	GOT1 (0.34)	SSTR4
	SCHEMBL20189774	0.83	GOT1 (0.34)	SSTR4
	SCHEMBL20189872	0.83	GRIN2B (0.36)	CYP1A2GRIN2BCYP2C19SSTR4HTR1A
	SCHEMBL20189870	0.83	GRIN2B (0.36)	CYP1A2GRIN2BCYP2C19SSTR4HTR1A
	SCHEMBL20202900	0.83	GRIN2B (0.45)	KDM4ECYP1A2GRIN2BCYP2C19ALDH1A1
	Hydrochloric Acid SCHEMBL18281002	0.82	GRIN2B (0.40)	GRIN2BSSTR4ALDH1A1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.