Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189766 | 0.82 | DUT (0.49) | DUTFBP1TPSAB1NAMPTALDH1A1 | |
| SCHEMBL21536109 | 0.80 | DUT (0.46) | DUTTPSAB1MTNR1ASLC9A3 | |
| SCHEMBL20189787 | 0.79 | DUT (0.61) | DUTFBP1NAMPTMTNR1AALDH1A1 | |
| SCHEMBL20189790 | 0.79 | DUT (0.61) | DUTFBP1TPSAB1ALDH1A1SLC9A3 | |
| SCHEMBL21536747 | 0.78 | DUT (0.54) | DUTFBP1MTNR1AALDH1A1MAPK1 | |
| SCHEMBL20190941 | 0.76 | DUT (0.58) | DUTFBP1TPSAB1ALDH1A1HTR1A | |
| SCHEMBL21522296 | 0.75 | DUT (0.58) | DUTALDH1A1MAPK1NPSR1 | |
| SCHEMBL20189610 | 0.74 | DUT (0.58) | DUTFBP1TPSAB1ALDH1A1MAPK1 | |
| SCHEMBL21536107 | 0.73 | DUT (0.46) | DUTTPSAB1MTNR1AALDH1A1SLC9A3 | |
| SCHEMBL20191126 | 0.73 | DUT (0.52) | DUTNAMPTMTNR1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168059-B2 | Amino sulfonyl compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-09 | — | — | US | disclosed |
| US-20190330158-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168059-B2 | Amino sulfonyl compounds | DPYD, DNPEP, DUT | DUT 3/4885FBP1 616/4885TPSAB1 3072/4885 |
| US-20190330158-A1 | AMINO SULFONYL COMPOUNDS | DPYD, DNPEP, DUT | DUT 3/4885FBP1 616/4885TPSAB1 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.