Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188522 | 0.74 | APLNR (0.49) | APLNR | |
| SCHEMBL20190853 | 0.74 | APLNR (0.52) | APLNR | |
| SCHEMBL20200871 | 0.66 | APLNR (0.57) | APLNR | |
| SCHEMBL20190228 | 0.64 | APLNR (0.81) | APLNR | |
| SCHEMBL20190203 | 0.64 | APLNR (0.53) | APLNR | |
| SCHEMBL20190696 | 0.63 | APLNR (0.72) | APLNR | |
| SCHEMBL20200320 | 0.62 | APLNR (0.74) | APLNR | |
| SCHEMBL20514217 | 0.61 | APLNR (0.52) | APLNR | |
| SCHEMBL20190094 | 0.61 | APLNR (1.00) | APLNR | |
| SCHEMBL20200907 | 0.60 | APLNR (0.52) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541792-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | Amgen Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |