Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188027 | 0.87 | GRIN2D (0.42) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL20188336 | 0.87 | PTPRA (0.39) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL20188290 | 0.86 | PTPRA (0.42) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL20188853 | 0.86 | PTPRA (0.38) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL22457613 | 0.86 | PTPRA (0.38) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL29735517 | 0.86 | CYP1A2 (0.39) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL20187735 | 0.84 | PTPRA (0.40) | PTPRAHDAC6HDAC1HRH2GAA | |
| SCHEMBL22457577 | 0.83 | CTSS (0.36) | PTPRAHDAC6HDAC1TDP1GAA | |
| SCHEMBL20189051 | 0.83 | CTSS (0.36) | PTPRAHDAC6HDAC1TDP1GAA | |
| SCHEMBL20188572 | 0.82 | PTPRA (0.39) | PTPRAHDAC6HDAC1KDM4EHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098344-A1 | PRODRUGS OF LANICEMINE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2018-05-31 | — | — | WO | disclosed |