Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562352 | 0.75 | ELANE (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL821494 | 0.75 | ELANE (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL17414527 | 0.75 | ELANE (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL26201200 | 0.75 | CNR2 (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL31320358 | 0.75 | ELANE (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL17388254 | 0.75 | ELANE (0.33) | NPC1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL24281979 | 0.70 | TDP1 (0.46) | SMN1; SMN2KMT2ATDP1KDM4E | |
| SCHEMBL821682 | 0.70 | ELANE (0.34) | NPC1SMN1; SMN2GAAPOLBNPSR1 | |
| SCHEMBL18944183 | 0.70 | TDP1 (0.46) | SMN1; SMN2KMT2ATDP1KDM4E | |
| SCHEMBL24281977 | 0.70 | ELANE (0.34) | NPC1SMN1; SMN2GAAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981068-B2 | Polymers which resist bacterial attachment | THE UNIVERSITY OF NOTTINGHAM (GB) | 2018-05-29 | — | — | US | disclosed |