SCHEMBL821494

SCHEMBL821494

CC(C)(C)C(=O)OCC1=CC(O)C2CC1C2(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
CNR2 P34972 6/20 0.33
NPC1 O15118 2/20 0.32
CNR1 P21554 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17388254 1.00 ELANE (0.33) ELANECNR2NPC1CNR1CYP1A2
SCHEMBL14562352 1.00 ELANE (0.33) ELANECNR2NPC1CNR1CYP1A2
SCHEMBL17414527 1.00 ELANE (0.33) ELANECNR2NPC1CNR1CYP1A2
SCHEMBL31320358 1.00 ELANE (0.33) ELANECNR2NPC1CNR1CYP1A2
SCHEMBL26201200 0.86 CNR2 (0.33) ELANECNR2NPC1CNR1CYP1A2
SCHEMBL26201119 0.85 GSTP1 (0.36) CNR2
SCHEMBL27026223 0.75 CNR2 (0.56) CNR2CNR1
SCHEMBL26201185 0.75 ELANE (0.32) ELANENPC1
SCHEMBL20192086 0.75 NPC1 (0.33) ELANENPC1CYP1A2CYP2C9CYP2C19
SCHEMBL24281977 0.74 ELANE (0.34) ELANECNR2NPC1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271908-A1 METHODS, PROCESSES, AND COMPOSITIONS FOR IMPROVED PREPARATION OF HU308 AND HU433 TETRA BIO-PHARMA INC. (CA) 2023-08-31 US disclosed
US-20230271908-A1 METHODS, PROCESSES, AND COMPOSITIONS FOR IMPROVED PREPARATION OF HU308 AND HU433 TETRA BIO-PHARMA INC. (CA) 2023-08-31 US disclosed
WO-2022061461-A1 METHODS, PROCESSES, AND COMPOSITIONS FOR IMPROVED PREPARATION OF HU308 AND HU433 TETRA BIO-PHARMA INC. (CA) 2022-03-31 WO disclosed
US-9428431-B2 Compositions comprising CB receptor agonists, uses thereof and methods for their preparation YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) 2016-08-30 US disclosed
US-9428431-B2 Compositions comprising CB receptor agonists, uses thereof and methods for their preparation YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) 2016-08-30 US disclosed
US-20110269842-A1 COMPOSITIONS COMPRISING CB RECEPTOR AGONISTS, USES THEREOF AND METHODS FOR THEIR PREPARATION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) 2011-11-03 US disclosed
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2007-03-15 US disclosed
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269842-A1 COMPOSITIONS COMPRISING CB RECEPTOR AGONISTS, USES THEREOF AND METHODS FOR THEIR PREPARATION CNR1, CNR2, ADRA2C ELANE 3436/4885CNR2 2/4885NPC1 734/4885
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions CNR2, CNR1, PDE8B ELANE 1995/4885CNR2 1/4885NPC1 2119/4885
US-20230271908-A1 METHODS, PROCESSES, AND COMPOSITIONS FOR IMPROVED PREPARATION OF HU308 AND HU433 CYP3A43, PRMT8, MGMT ELANE 1084/4885CNR2 2295/4885NPC1 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.