Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21031798 | 0.81 | AAK1 (0.47) | AAK1KCNQ4KCNQ5CNR2MAPKAPK2 | |
| SCHEMBL18623980 | 0.81 | MEN1 (0.61) | MEN1MMP14KMT2AMAOATERT | |
| SCHEMBL5869497 | 0.74 | CNR2 (0.44) | AAK1KCNQ4KCNQ5CNR2 | |
| SCHEMBL28159201 | 0.71 | KCNQ4 (0.42) | AAK1KCNQ4KCNQ5 | |
| SCHEMBL17369611 | 0.69 | KCNQ4 (0.48) | AAK1KCNQ4KCNQ5 | |
| SCHEMBL7344988 | 0.69 | AAK1 (0.47) | AAK1KCNQ4KCNQ5 | |
| SCHEMBL27915724 | 0.69 | AAK1 (0.46) | AAK1KCNQ4KCNQ5 | |
| SCHEMBL23093142 | 0.69 | SMN1; SMN2 (0.47) | MEN1KMT2AKCNQ4KCNQ5CNR2 | |
| SCHEMBL19930251 | 0.69 | PPARA (0.44) | KCNQ4KCNQ5CNR2 | |
| SCHEMBL23093133 | 0.69 | CNR2 (0.43) | METAP2KCNQ4KCNQ5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9980936-B2 | BH4 antagonists and methods related thereto | EMORY UNIVERSITY (US) | 2018-05-29 | — | — | US | disclosed |