Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16643863 | 0.87 | PTPN1 (0.54) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL20997581 | 0.77 | ALDH1A1 (0.44) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL21677057 | 0.76 | POLB (0.42) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL16643864 | 0.74 | MEN1 (0.50) | L3MBTL1CYP2C19EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL25631005 | 0.73 | KDM4E (0.52) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL25631004 | 0.73 | KDM4E (0.52) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL23185467 | 0.73 | EPHX2 (0.46) | EPHX2ALDH1A1 | |
| SCHEMBL4145613 | 0.73 | PTPN1 (0.55) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL12197944 | 0.72 | ALDH1A1 (0.60) | PTPN1POLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL19116660 | 0.71 | TDP1 (0.59) | PTPN1POLBNPSR1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981046-B2 | Drug-conjugates, conjugation methods, and uses thereof | Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) | 2018-05-29 | — | — | US | disclosed |