Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | OTC | P00480 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447017 | 0.81 | NOS3 (0.42) | NOS3NOS1NOS2TLR2SMN1; SMN2 | |
| SCHEMBL20192884 | 0.80 | NOS3 (0.44) | NOS3NOS1NOS2TLR2OTC | |
| SCHEMBL16447373 | 0.79 | NOS3 (0.42) | NOS3NOS1NOS2TLR2SMN1; SMN2 | |
| SCHEMBL16446597 | 0.79 | TSHR (0.53) | NOS3NOS1NOS2TLR2SMN1; SMN2 | |
| SCHEMBL31369833 | 0.79 | GSR (0.55) | NOS2NOD1OTCTSHRGSR | |
| SCHEMBL1316628 | 0.78 | GSR (0.52) | NOS3NOS1NOS2TLR2GSR | |
| SCHEMBL4018310 | 0.78 | GSR (0.52) | NOS3NOS1NOS2TLR2GSR | |
| SCHEMBL20192952 | 0.77 | NOS3 (0.42) | NOS3NOS1NOS2SMN1; SMN2GSR | |
| Hydrochloric Acid SCHEMBL21332552 | 0.77 | NOS3 (0.50) | NOS3NOS1NOS2TLR2GSR | |
| Hydrochloric Acid SCHEMBL21332553 | 0.77 | NOS3 (0.50) | NOS3NOS1NOS2TLR2GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |