Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFPT1 | Q06210 | 1/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20192910 | 0.83 | PRSS1 (0.35) | CTHPRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL16447372 | 0.80 | GFPT1 (0.34) | GFPT1 | |
| SCHEMBL20178594 | 0.80 | GFPT1 (0.34) | GFPT1 | |
| SCHEMBL20192957 | 0.79 | GFPT1 (0.37) | GFPT1CTHLMNAGSRMMP2 | |
| SCHEMBL16446798 | 0.79 | GFPT1 (0.40) | GFPT1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL16446924 | 0.79 | SLC1A3 (0.37) | GFPT1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL20178596 | 0.79 | SLC1A3 (0.37) | GFPT1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL23817748 | 0.76 | GFPT1 (0.41) | GFPT1CTHLMNAGSRMMP2 | |
| SCHEMBL23455605 | 0.75 | MEN1 (0.46) | GFPT1CASR | |
| SCHEMBL23455458 | 0.75 | MEN1 (0.46) | GFPT1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |