Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 11/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608611 | 0.89 | CHUK (0.42) | CHUKARXDHMAP3K14 | |
| SCHEMBL20193164 | 0.89 | CHUK (0.37) | CHUKAR | |
| SCHEMBL20193239 | 0.88 | CHUK (0.60) | CHUKMAP3K14 | |
| SCHEMBL20193161 | 0.81 | CHUK (0.42) | CHUK | |
| SCHEMBL20193280 | 0.81 | CHUK (0.60) | CHUKMAP3K14 | |
| SCHEMBL16608610 | 0.77 | DGAT1 (0.37) | CHUKAR | |
| SCHEMBL16608662 | 0.77 | CHUK (0.59) | CHUKMAP3K14 | |
| SCHEMBL19114479 | 0.76 | CHUK (0.58) | CHUKMAP3K14 | |
| SCHEMBL20193234 | 0.76 | CHUK (0.35) | CHUK | |
| SCHEMBL20193220 | 0.75 | CHUK (0.32) | CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |