Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19114705 | 0.82 | TOP2A (0.32) | TOP2ATOP2B | |
| SCHEMBL19114567 | 0.70 | TOP2A (0.37) | TOP2ATOP2B | |
| SCHEMBL20191342 | 0.70 | DGAT1 (0.34) | TOP2ATOP2B | |
| SCHEMBL20193224 | 0.69 | CHUK (0.30) | — | |
| SCHEMBL18013735 | 0.68 | TOP2A (0.31) | TOP2ATOP2B | |
| SCHEMBL16608484 | 0.68 | TOP2A (0.36) | TOP2ATOP2B | |
| SCHEMBL20193169 | 0.66 | — | — | |
| SCHEMBL20193216 | 0.66 | CHUK (0.40) | — | |
| SCHEMBL19114707 | 0.63 | CHUK (0.30) | — | |
| SCHEMBL19629572 | 0.62 | MAP3K14 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |