⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482908 | 1.00 | — | — | |
| SCHEMBL2014253 | 0.86 | — | — | |
| SCHEMBL2017827 | 0.82 | — | — | |
| SCHEMBL2018171 | 0.81 | MAPK14 (0.50) | — | |
| SCHEMBL12985418 | 0.77 | — | — | |
| SCHEMBL2020157 | 0.77 | MAPK14 (0.55) | — | |
| SCHEMBL2015312 | 0.76 | — | — | |
| SCHEMBL12632940 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL2016291 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL12632939 | 0.75 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180123-B2 | N-link hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20150182513-A1 | N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2015-07-02 | — | — | US | disclosed |
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |