Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.78 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.78 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.78 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388722 | 0.92 | NR1H2 (0.86) | RXRANR1H2NR1H3BRD4RIPK3 | |
| SCHEMBL2389217 | 0.89 | RXRA (0.70) | RXRANR1H2NR1H3BRD4RIPK3 | |
| SCHEMBL2389317 | 0.88 | RXRA (0.69) | RXRANR1H2NR1H3BRD4 | |
| SCHEMBL2390377 | 0.88 | NR1H2 (1.00) | RXRANR1H2NR1H3RIPK3MAPK14 | |
| SCHEMBL2390225 | 0.86 | RXRA (0.80) | RXRANR1H2NR1H3RIPK3MAPK14 | |
| SCHEMBL2387937 | 0.85 | RXRA (0.78) | RXRANR1H2NR1H3BRD4MAPK14 | |
| SCHEMBL2389166 | 0.85 | RXRA (0.71) | RXRANR1H2NR1H3BRD4ALDH1A1 | |
| SCHEMBL2387438 | 0.85 | RXRA (0.70) | RXRANR1H2NR1H3BRD4MAPK14 | |
| SCHEMBL14214290 | 0.84 | RXRA (0.81) | RXRANR1H2NR1H3MAPK14ALDH1A1 | |
| SCHEMBL2387653 | 0.84 | NR1H2 (0.74) | RXRANR1H2NR1H3BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981913-B2 | Liver X receptor (LXR) modulators | RALEXAR THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |