Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401728 | 0.92 | HTT (0.65) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL22131044 | 0.89 | POLB (0.63) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL18675331 | 0.89 | POLB (0.54) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL21299134 | 0.88 | POLB (0.53) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL20414533 | 0.86 | POLB (0.57) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL22099372 | 0.85 | POLB (0.54) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL14400544 | 0.85 | HTT (0.73) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL19434087 | 0.84 | POLB (0.62) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL22099043 | 0.83 | POLB (0.49) | HTTPOLBAPEX1TDP1PPARA | |
| SCHEMBL16982216 | 0.83 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2933308-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-05-30 | — | — | EP | disclosed |