SCHEMBL18675331

SCHEMBL18675331

C=C(C)C(=O)OCCCOc1ccc(/C=C/c2ccc(-c3ccc(OC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
APEX1 P27695 1/20 0.54
HTT P42858 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PPARA Q07869 6/20 0.42
ELANE P08246 1/20 0.41
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
TTR P02766 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.39
ALB P02768 1/20 0.39
ATM Q13315 1/20 0.39
PTPN1 P18031 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21299134 0.94 POLB (0.53) POLBAPEX1HTTTDP1PPARA
SCHEMBL689051 0.92 POLB (0.62) POLBAPEX1HTTTDP1PPARA
SCHEMBL22099043 0.92 POLB (0.49) POLBAPEX1HTTTDP1PPARA
SCHEMBL22131044 0.91 POLB (0.63) POLBAPEX1HTTTDP1PPARA
SCHEMBL22099389 0.90 POLB (0.49) POLBAPEX1HTTTDP1PPARA
SCHEMBL20194337 0.89 HTT (0.55) POLBAPEX1HTTTDP1PPARA
SCHEMBL22098928 0.89 POLB (0.51) POLBAPEX1HTTTDP1PPARA
SCHEMBL690787 0.88 HTT (0.67) POLBAPEX1HTTTDP1ELANE
SCHEMBL22098903 0.88 POLB (0.49) POLBAPEX1HTTTDP1PPARA
SCHEMBL12991026 0.87 POLB (0.59) POLBAPEX1HTTTDP1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10394084-B2 Liquid crystal display and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-27 US disclosed
US-20170090250-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-30 US disclosed
US-20170090250-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-30 US disclosed