SCHEMBL2019462

SCHEMBL2019462

CCCCc1ccccc1NC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.58
SLC16A3 O15427 5/20 0.52
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15861767 0.95 POLB (0.56) POLBSLC16A3HDAC3HDAC4HDAC1
SCHEMBL2026770 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL2025660 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL2021245 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL2023026 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL11458675 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL2018888 0.93 SLC16A3 (0.57) POLBSLC16A3
SCHEMBL2022897 0.89 POLB (0.53) POLBSLC16A3HDAC3HDAC4HDAC1
SCHEMBL29580948 0.88 POLB (0.64) POLBSLC16A3HDAC3HDAC4HDAC1
SCHEMBL15094123 0.88 POLB (0.64) POLBSLC16A3HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405319-B2 Process for the preparation of carbamates COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-07-29 US claimed
US-20070270605-A1 Process for the preparation of carbamates COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-11-22 US claimed
EP-0016441-B1 A METHOD FOR THE PREPARATION OF A MIXTURE OF DIPHENYL METHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES ATLANTIC RICHFIELD COMPANY (US) 1982-05-12 EP claimed
US-4230877-A ACID CATALYZED CONDENSATION OF AN N-ARYL CARBAMIC ACID ESTER WITH A CARBONYL COMPOUND ATLANTIC RICHFIELD COMPANY (US) 1980-10-28 US claimed
EP-0016441-A2 A method for the preparation of a mixture of diphenyl methane dicarbamates and polymethylene polyphenyl carbamates ATLANTIC RICHFIELD COMPANY (US) 1980-10-01 EP claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
EP-3372579-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2020-10-28 EP disclosed
EP-3536683-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2019-09-11 EP disclosed
EP-3527600-A1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-08-21 EP disclosed
EP-0016441-B1 A METHOD FOR THE PREPARATION OF A MIXTURE OF DIPHENYL METHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES ATLANTIC RICHFIELD COMPANY (US) 1982-05-12 EP disclosed
US-4266070-A CARBONYLS OF COBALT, MOLYBDENUM, TITANIUM, RHODIUM, IRON, NICKEL AND IRIDIUM AS CATALYSTS FOR THE CARBONYLATION OF PRIMARY OR SECONDARY AMINES AND ALCOHOLS TO FORM CARBAMATES HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-05-05 US disclosed
US-4260781-A Process for the manufacture of carbamates HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-04-07 US disclosed
US-4258201-A CATALYTIC CARBONYLATION OF PRIMARY OR SECONDARY AMINES WITH CARBON MONOXIDE AND ALCOHOLS HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-03-24 US disclosed
US-4242520-A ONE-STEP CARBONYLATION OF AMINES IN THE PRESENCE OF A DISULFIDE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-12-30 US disclosed
US-4230877-A ACID CATALYZED CONDENSATION OF AN N-ARYL CARBAMIC ACID ESTER WITH A CARBONYL COMPOUND ATLANTIC RICHFIELD COMPANY (US) 1980-10-28 US disclosed
EP-0016441-A2 A method for the preparation of a mixture of diphenyl methane dicarbamates and polymethylene polyphenyl carbamates ATLANTIC RICHFIELD COMPANY (US) 1980-10-01 EP disclosed
EP-0014103-A2 Improved process for the manufacture of carbamates THE HALCON SD GROUP, INC. (US) 1980-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B POLB 3507/4885SLC16A3 918/4885HDAC3 86/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B POLB 3251/4885SLC16A3 1156/4885HDAC3 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.